NovaBone® Morsels
- Particulate product made up of a crystalline composite Calcium Phosphosilicate
- 100% synthetic and resorbable
- Osteostimulatory effect of material results in stimulation of osteoblast proliferation
- Sustained resorption that is completed over a 12 - 18 month period
- Pore size: 0.05 mm - 0.10 mm
- Particle size: 0.5 mm - 1.0 mm
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NovaBone® Morsels (1.3 CC)
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NovaBone® Morsels is a particulate product made up of a crystalline composite calcium phosphosilicate. The particle size ranges from 0.5 mm - 1.0 mm with pore sizes ranging from 0.05 mm - 0.10 mm. The pore size results in slow and sustained resorption that is completed over a 12 - 18 month period. The morsels have an "osteostimulative" effect similar to NovaBone® Dental Putty.
Osteostimulative & Osteoconductive
Unlike most synthetic grafts that are only osteoconductive, bioactive NovaBone® Morsels also has an "osteostimulative" effect. After implantation, surface reactions result in absorption of the graft material, a controlled release of Si, Ca, and P ions, and concurrent new bone formation. These surface reactions result in an osteostimulative effect, defined as the stimulation of osteoblast proliferation in vitro as evidenced by increased DNA content and elevated osteocalcin and alkaline phosphatase levels. In vitro gene array analysis has confirmed that when human primary osteoblasts are exposed to extracts of CPS, upregulation of several gene families occurs.
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Published Studies
Clinical and radiographic evaluation and comparison of bioactive bone alloplast morsels when used alone and in combination with platelet-rich fibrin in the treatment of periodontal intrabony defects-A randomized controlled trial.
Bodhare GH, Kolte AP, Kolte RA, Shirke PY.
J Periodontol. 2019 Jun;90(6):584-594.
Published Case Series
Sinus Augmentation Utilizing Calcium Phosphosilicate Biomaterial Followed by Delayed Implant Rehabilitation: Radiological and Clinical Analyses.
Rayapati Dilip Kumar, Honey Verma, NT Prashanth, ES Shobha
IJOICR. September-December 2013;4(3):102-107